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Structurally- and dynamically-driven allostery of the chymotrypsin-like proteases of SARS, Dengue and Zika viruses

Coronavirus 3C-like and Flavivirus NS2B-NS3 proteases utilize the chymotrypsin fold to harbor their catalytic machineries but also contain additional domains/co-factors. Over the past decade, we aimed to decipher how the extra domains/co-factors mediate the catalytic machineries of SARS 3C-like, Den...

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Detalles Bibliográficos
Autores principales:	Lim, Liangzhong, Gupta, Garvita, Roy, Amrita, Kang, Jian, Srivastava, Shagun, Shi, Jiahai, Song, Jianxing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Ltd. 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7111307/ https://www.ncbi.nlm.nih.gov/pubmed/30217495 http://dx.doi.org/10.1016/j.pbiomolbio.2018.08.009

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