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Synthesis, modification and docking studies of 5-sulfonyl isatin derivatives as SARS-CoV 3C-like protease inhibitors

The Severe Acute Respiratory Syndrome (SARS) is a serious life-threatening and strikingly mortal respiratory illness caused by SARS-CoV. SARS-CoV which contains a chymotrypsin-like main protease analogous to that of the main picornavirus protease, 3CL(pro). 3CL(pro) plays a pivotal role in the viral...

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Detalles Bibliográficos
Autores principales:	Liu, Wei, Zhu, He-Min, Niu, Guo-Jun, Shi, En-Zhi, Chen, Jie, Sun, Bo, Chen, Wei-Qiang, Zhou, Hong-Gang, Yang, Cheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Ltd. 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7111328/ https://www.ncbi.nlm.nih.gov/pubmed/24316352 http://dx.doi.org/10.1016/j.bmc.2013.11.028

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