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Synthesis and inhibitory activity of sialic acid derivatives targeted at viral sialate-O-acetylesterases
A series of sialosides modified at the 4- and 9-hydroxy group were synthesised and tested for inhibition of the viral haemagglutinin-esterase activity from various Orthomyxoviruses and Coronaviruses. While no inhibition of the sialate-4-O-acetylesterases from mouse hepatitis virus strain S or sialod...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier Masson SAS.
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7111470/ https://www.ncbi.nlm.nih.gov/pubmed/21524502 http://dx.doi.org/10.1016/j.ejmech.2011.04.008 |