Analysis of Hi-C data using SIP effectively identifies loops in organisms from C. elegans to mammals

Chromatin loops are a major component of 3D nuclear organization, visually apparent as intense point-to-point interactions in Hi-C maps. Identification of these loops is a critical part of most Hi-C analyses. However, current methods often miss visually evident CTCF loops in Hi-C data sets from mamm...

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Detalles Bibliográficos
Autores principales: Rowley, M. Jordan, Poulet, Axel, Nichols, Michael H., Bixler, Brianna J., Sanborn, Adrian L., Brouhard, Elizabeth A., Hermetz, Karen, Linsenbaum, Hannah, Csankovszki, Gyorgyi, Lieberman Aiden, Erez, Corces, Victor G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7111518/
https://www.ncbi.nlm.nih.gov/pubmed/32127418
http://dx.doi.org/10.1101/gr.257832.119

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