Cargando…
Rhubarb and Astragalus Capsule Attenuates Renal Interstitial Fibrosis in Rats with Unilateral Ureteral Obstruction by Alleviating Apoptosis through Regulating Transforming Growth Factor beta1 (TGF-β1)/p38 Mitogen-Activated Protein Kinases (p38 MAPK) Pathway
BACKGROUND: Rhubarb and astragalus capsule (RAC) has been used in the clinical treatment of chronic kidney disease for decades. However, the mechanism of RAC has not been fully elucidated. This study aimed to investigate the protective effect and mechanisms of RAC on unilateral ureteral obstruction...
Autores principales: | Zeng, Xian, Cai, Guozhen, Liang, Taolin, Li, Qingqing, Yang, Yufang, Zhong, Xiaobin, Zou, Xiaoqin, Qin, Mengyuan, Mi, Zhengcheng |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Scientific Literature, Inc.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7111584/ https://www.ncbi.nlm.nih.gov/pubmed/32205836 http://dx.doi.org/10.12659/MSM.920720 |
Ejemplares similares
-
Ginaton injection alleviates cisplatin-induced renal interstitial fibrosis in rats via inhibition of apoptosis through regulation of the p38MAPK/TGF-β1 and p38MAPK/HIF-1α pathways
por: Liang, Taolin, et al.
Publicado: (2021) -
The activation of p38alpha, and not p38beta, mitogen-activated protein kinase is required for ischemic preconditioning
por: Sicard, Pierre, et al.
Publicado: (2010) -
P38 Mitogen-activated Protein Kinase and Parkinson’s Disease
por: He, Jianying, et al.
Publicado: (2018) -
p38γ and p38δ Mitogen Activated Protein Kinases (MAPKs), New Stars in the MAPK Galaxy
por: Escós, Alejandra, et al.
Publicado: (2016) -
Activation of p38 Mitogen-Activated Protein Kinase in Gaucher’s Disease
por: Kitatani, Kazuyuki, et al.
Publicado: (2015)