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MEDICAL MANAGEMENT OF HIV DISEASE IN CHILDREN

Pediatric HIV infection in the United States has evolved from a rapidly progressive, fatal disease in the early years of the epidemic to a chronic infection with prolonged survival. Many children with perinatally acquired infection survive to 8 years of age and older. The development of highly activ...

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Detalles Bibliográficos
Autores principales: Laufer, Marcelo, Scott, Gwendolyn B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: W. B. Saunders Company. Published by Elsevier Inc. 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7111615/
https://www.ncbi.nlm.nih.gov/pubmed/10697645
http://dx.doi.org/10.1016/S0031-3955(05)70198-X
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author Laufer, Marcelo
Scott, Gwendolyn B.
author_facet Laufer, Marcelo
Scott, Gwendolyn B.
author_sort Laufer, Marcelo
collection PubMed
description Pediatric HIV infection in the United States has evolved from a rapidly progressive, fatal disease in the early years of the epidemic to a chronic infection with prolonged survival. Many children with perinatally acquired infection survive to 8 years of age and older. The development of highly active antiretroviral therapy (HAART), measurement of viral load, and availability of prophylactic medications to prevent certain opportunistic infections have dramatically altered the management of HIV infection. A total of 14 antiretroviral agents have been approved by the US Food and Drug Administration, 10 of which have been approved for use in pediatrics. Several new drugs are in various stages of development. This article discusses special issues in the medical management of children with HIV infection, including routine care, immunization, and treatment of some of the more common organ-specific manifestations, disclosure of the HIV diagnosis, pain management, palliative care, and the management of infants born to HIV-seropositive women.
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spelling pubmed-71116152020-04-02 MEDICAL MANAGEMENT OF HIV DISEASE IN CHILDREN Laufer, Marcelo Scott, Gwendolyn B. Pediatr Clin North Am Article Pediatric HIV infection in the United States has evolved from a rapidly progressive, fatal disease in the early years of the epidemic to a chronic infection with prolonged survival. Many children with perinatally acquired infection survive to 8 years of age and older. The development of highly active antiretroviral therapy (HAART), measurement of viral load, and availability of prophylactic medications to prevent certain opportunistic infections have dramatically altered the management of HIV infection. A total of 14 antiretroviral agents have been approved by the US Food and Drug Administration, 10 of which have been approved for use in pediatrics. Several new drugs are in various stages of development. This article discusses special issues in the medical management of children with HIV infection, including routine care, immunization, and treatment of some of the more common organ-specific manifestations, disclosure of the HIV diagnosis, pain management, palliative care, and the management of infants born to HIV-seropositive women. W. B. Saunders Company. Published by Elsevier Inc. 2000-02-01 2005-07-15 /pmc/articles/PMC7111615/ /pubmed/10697645 http://dx.doi.org/10.1016/S0031-3955(05)70198-X Text en © 2000 W. B. Saunders Company Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Laufer, Marcelo
Scott, Gwendolyn B.
MEDICAL MANAGEMENT OF HIV DISEASE IN CHILDREN
title MEDICAL MANAGEMENT OF HIV DISEASE IN CHILDREN
title_full MEDICAL MANAGEMENT OF HIV DISEASE IN CHILDREN
title_fullStr MEDICAL MANAGEMENT OF HIV DISEASE IN CHILDREN
title_full_unstemmed MEDICAL MANAGEMENT OF HIV DISEASE IN CHILDREN
title_short MEDICAL MANAGEMENT OF HIV DISEASE IN CHILDREN
title_sort medical management of hiv disease in children
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7111615/
https://www.ncbi.nlm.nih.gov/pubmed/10697645
http://dx.doi.org/10.1016/S0031-3955(05)70198-X
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