Identification of a pH sensor in Influenza hemagglutinin using X-ray crystallography

Hemagglutnin (HA) mediates entry of influenza virus through a series of conformational changes triggered by the low pH of the endosome. The residue or combination of residues acting as pH sensors has not yet been fully elucidated. In this work, we assay pH effects on the structure of H5 HA by soakin...

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Detalles Bibliográficos
Autores principales: Antanasijevic, Aleksandar, Durst, Matthew A., Lavie, Arnon, Caffrey, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7111647/
https://www.ncbi.nlm.nih.gov/pubmed/31689502
http://dx.doi.org/10.1016/j.jsb.2019.107412

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7111647/
https://www.ncbi.nlm.nih.gov/pubmed/31689502
http://dx.doi.org/10.1016/j.jsb.2019.107412

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