Jubanines F–J, cyclopeptide alkaloids from the roots of Ziziphus jujuba

Five Ib-type cyclopeptide alkaloids, jubanines F–J (1–5), and three known compounds, nummularine B (6), daechuine-S3 (7), and mucronine K (8) were isolated from the roots of Ziziphus jujuba. Their structures were fully characterized by spectroscopic analyses in combination with chemical derivatizati...

Descripción completa

Detalles Bibliográficos
Autores principales: Kang, Kyo Bin, Ming, Gao, Kim, Geum Jin, Ha, Thi-Kim-Quy, Choi, Hyukjae, Oh, Won Keun, Sung, Sang Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7111685/
https://www.ncbi.nlm.nih.gov/pubmed/26361730
http://dx.doi.org/10.1016/j.phytochem.2015.09.001
_version_ 1783513332794261504
author Kang, Kyo Bin
Ming, Gao
Kim, Geum Jin
Ha, Thi-Kim-Quy
Choi, Hyukjae
Oh, Won Keun
Sung, Sang Hyun
author_facet Kang, Kyo Bin
Ming, Gao
Kim, Geum Jin
Ha, Thi-Kim-Quy
Choi, Hyukjae
Oh, Won Keun
Sung, Sang Hyun
author_sort Kang, Kyo Bin
collection PubMed
description Five Ib-type cyclopeptide alkaloids, jubanines F–J (1–5), and three known compounds, nummularine B (6), daechuine-S3 (7), and mucronine K (8) were isolated from the roots of Ziziphus jujuba. Their structures were fully characterized by spectroscopic analyses in combination with chemical derivatization. Compounds 1–3, and 6 were evaluated for their antiviral activity against the porcine epidemic diarrhea virus (PEDV). Compounds 2, 3, and 6 showed potent inhibitory effects on PEDV replication.
format Online
Article
Text
id pubmed-7111685
institution National Center for Biotechnology Information
language English
publishDate 2015
publisher Elsevier Ltd.
record_format MEDLINE/PubMed
spelling pubmed-71116852020-04-02 Jubanines F–J, cyclopeptide alkaloids from the roots of Ziziphus jujuba Kang, Kyo Bin Ming, Gao Kim, Geum Jin Ha, Thi-Kim-Quy Choi, Hyukjae Oh, Won Keun Sung, Sang Hyun Phytochemistry Article Five Ib-type cyclopeptide alkaloids, jubanines F–J (1–5), and three known compounds, nummularine B (6), daechuine-S3 (7), and mucronine K (8) were isolated from the roots of Ziziphus jujuba. Their structures were fully characterized by spectroscopic analyses in combination with chemical derivatization. Compounds 1–3, and 6 were evaluated for their antiviral activity against the porcine epidemic diarrhea virus (PEDV). Compounds 2, 3, and 6 showed potent inhibitory effects on PEDV replication. Elsevier Ltd. 2015-11 2015-09-08 /pmc/articles/PMC7111685/ /pubmed/26361730 http://dx.doi.org/10.1016/j.phytochem.2015.09.001 Text en Copyright © 2015 Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Kang, Kyo Bin
Ming, Gao
Kim, Geum Jin
Ha, Thi-Kim-Quy
Choi, Hyukjae
Oh, Won Keun
Sung, Sang Hyun
Jubanines F–J, cyclopeptide alkaloids from the roots of Ziziphus jujuba
title Jubanines F–J, cyclopeptide alkaloids from the roots of Ziziphus jujuba
title_full Jubanines F–J, cyclopeptide alkaloids from the roots of Ziziphus jujuba
title_fullStr Jubanines F–J, cyclopeptide alkaloids from the roots of Ziziphus jujuba
title_full_unstemmed Jubanines F–J, cyclopeptide alkaloids from the roots of Ziziphus jujuba
title_short Jubanines F–J, cyclopeptide alkaloids from the roots of Ziziphus jujuba
title_sort jubanines f–j, cyclopeptide alkaloids from the roots of ziziphus jujuba
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7111685/
https://www.ncbi.nlm.nih.gov/pubmed/26361730
http://dx.doi.org/10.1016/j.phytochem.2015.09.001
work_keys_str_mv AT kangkyobin jubaninesfjcyclopeptidealkaloidsfromtherootsofziziphusjujuba
AT minggao jubaninesfjcyclopeptidealkaloidsfromtherootsofziziphusjujuba
AT kimgeumjin jubaninesfjcyclopeptidealkaloidsfromtherootsofziziphusjujuba
AT hathikimquy jubaninesfjcyclopeptidealkaloidsfromtherootsofziziphusjujuba
AT choihyukjae jubaninesfjcyclopeptidealkaloidsfromtherootsofziziphusjujuba
AT ohwonkeun jubaninesfjcyclopeptidealkaloidsfromtherootsofziziphusjujuba
AT sungsanghyun jubaninesfjcyclopeptidealkaloidsfromtherootsofziziphusjujuba

Ejemplares similares