Solution-phase synthesis of 2-cyano and 2-amido aziridinyl peptides

Starting from a library of 2-l-α-amino acyl (E)-acrylonitriles, different short 2-cyano and 2-amido aziridinyl peptides, potential protease inhibitors, were obtained under parallel solution-phase conditions. The transformations include careful selection of conditions for aziridine deprotection and c...

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Detalles Bibliográficos
Autores principales: Fioravanti, Stefania, Massari, Davide, Morreale, Alberto, Pellacani, Lucio, Tardella, Paolo A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2008
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7111778/
https://www.ncbi.nlm.nih.gov/pubmed/32287417
http://dx.doi.org/10.1016/j.tet.2008.01.098

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7111778/
https://www.ncbi.nlm.nih.gov/pubmed/32287417
http://dx.doi.org/10.1016/j.tet.2008.01.098

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