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Solution-phase synthesis of 2-cyano and 2-amido aziridinyl peptides
Starting from a library of 2-l-α-amino acyl (E)-acrylonitriles, different short 2-cyano and 2-amido aziridinyl peptides, potential protease inhibitors, were obtained under parallel solution-phase conditions. The transformations include careful selection of conditions for aziridine deprotection and c...
Autores principales: | Fioravanti, Stefania, Massari, Davide, Morreale, Alberto, Pellacani, Lucio, Tardella, Paolo A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Ltd.
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7111778/ https://www.ncbi.nlm.nih.gov/pubmed/32287417 http://dx.doi.org/10.1016/j.tet.2008.01.098 |
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