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Testing the modularity of the N-terminal amphipathic helix conserved in picornavirus 2C proteins and hepatitis C NS5A protein
The N-terminal region of the picornaviral 2C protein is predicted to fold into an amphipathic α-helix that is responsible for the protein's association with membranes in the viral RNA replication complex. We have identified a similar sequence in the N-terminal region of NS5A of hepaciviruses th...
Autores principales: | Teterina, Natalya L., Gorbalenya, Alexander E., Egger, Denise, Bienz, Kurt, Rinaudo, Mario S., Ehrenfeld, Ellie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Academic Press
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7111807/ https://www.ncbi.nlm.nih.gov/pubmed/16226781 http://dx.doi.org/10.1016/j.virol.2005.08.044 |
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