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Immunogenicity of a DNA-launched replicon-based canine parvovirus DNA vaccine expressing VP2 antigen in dogs

A replicon-based DNA vaccine encoding VP2 gene of canine parvovirus (CPV) was developed by cloning CPV-VP2 gene into a replicon-based DNA vaccine vector (pAlpha). The characteristics of a replicon-based DNA vaccine like, self-amplification of transcripts and induction of apoptosis were analyzed in t...

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Detalles Bibliográficos
Autores principales: Dahiya, Shyam S., Saini, Mohini, Kumar, Pankaj, Gupta, Praveen K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Ltd. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7111809/
https://www.ncbi.nlm.nih.gov/pubmed/22349592
http://dx.doi.org/10.1016/j.rvsc.2012.01.017