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Mutagenesis of the murine hepatitis virus nsp1-coding region identifies residues important for protein processing, viral RNA synthesis, and viral replication

Despite ongoing research investigating mechanisms of coronavirus replication, functions of many viral nonstructural proteins (nsps) remain unknown. In the current study, a reverse genetic approach was used to define the role of the 28-kDa amino-terminal product (nsp1) of the gene 1 polyprotein durin...

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Detalles Bibliográficos
Autores principales:	Brockway, Sarah M., Denison, Mark R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Inc. 2005
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7111834/ https://www.ncbi.nlm.nih.gov/pubmed/16051301 http://dx.doi.org/10.1016/j.virol.2005.06.035

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