An efficient synthesis of 3-indolyl-3-hydroxy oxindoles and 3,3-di(indolyl)indolin-2-ones catalyzed by sulfonated β-CD as a supramolecular catalyst in water

Sulfonated-β-cyclodextrin (β-CD-SO(3)H) promoted efficient and fast electrophilic substitution reaction of indoles with various isatins reflux in water is reported affording various 3-indolyl-3-hydroxy oxindoles and 3,3-di(indolyl)indolin-2-ones in good to excellent yields in short reaction time.

Detalles Bibliográficos
Autores principales: Tayade, Yogesh A., Patil, Dipak R., Wagh, Yogesh B., Jangle, Asha D., Dalal, Dipak S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7111843/
https://www.ncbi.nlm.nih.gov/pubmed/32287446
http://dx.doi.org/10.1016/j.tetlet.2014.12.012
Descripción
Sumario:Sulfonated-β-cyclodextrin (β-CD-SO(3)H) promoted efficient and fast electrophilic substitution reaction of indoles with various isatins reflux in water is reported affording various 3-indolyl-3-hydroxy oxindoles and 3,3-di(indolyl)indolin-2-ones in good to excellent yields in short reaction time.

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