Cargando…

Identification of aromatic amino acid residues in conserved region VI of the large polymerase of vesicular stomatitis virus is essential for both guanine-N-7 and ribose 2'-O methyltransferases

Non-segmented negative-sense RNA viruses possess a unique mechanism for mRNA cap methylation. For vesicular stomatitis virus, conserved region VI in the large (L) polymerase protein catalyzes both guanine-N-7 (G-N-7) and ribose 2'-O (2'-O) methyltransferases, and the two methylases share a...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Xiaodong, Wei, Yongwei, Ma, Yuanmei, Hu, Songhua, Li, Jianrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7111938/
https://www.ncbi.nlm.nih.gov/pubmed/20961592
http://dx.doi.org/10.1016/j.virol.2010.09.017