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Transmissible gastroenteritis virus (TGEV)-based vectors with engineered murine tropism express the rotavirus VP7 protein and immunize mice against rotavirus

A coronavirus vector based on the genome of the porcine transmissible gastroenteritis virus (TGEV) expressing the rotavirus VP7 protein was constructed to immunize and protect against rotavirus infections in a murine model. The tropism of this TGEV-derived vector was modified by replacing the spike...

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Detalles Bibliográficos
Autores principales: Ribes, Juan Manuel, Ortego, Javier, Ceriani, Juan, Montava, Rebeca, Enjuanes, Luis, Buesa, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7111951/
https://www.ncbi.nlm.nih.gov/pubmed/21094967
http://dx.doi.org/10.1016/j.virol.2010.10.036

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