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Human monoclonal antibodies to SARS-coronavirus inhibit infection by different mechanisms
SARS-CoV causes an acute infection making targeted passive immunotherapy an attractive treatment strategy. We previously generated human mAbs specific to the S1 region of SARS-CoV S protein. These mAbs bind epitopes within the receptor binding domain (RBD) or upstream of the RBD. We show that mAbs r...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Inc.
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7111986/ https://www.ncbi.nlm.nih.gov/pubmed/19748648 http://dx.doi.org/10.1016/j.virol.2009.07.028 |