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Human monoclonal antibodies to SARS-coronavirus inhibit infection by different mechanisms

SARS-CoV causes an acute infection making targeted passive immunotherapy an attractive treatment strategy. We previously generated human mAbs specific to the S1 region of SARS-CoV S protein. These mAbs bind epitopes within the receptor binding domain (RBD) or upstream of the RBD. We show that mAbs r...

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Detalles Bibliográficos
Autores principales:	Coughlin, Melissa M., Babcook, John, Prabhakar, Bellur S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Inc. 2009
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7111986/ https://www.ncbi.nlm.nih.gov/pubmed/19748648 http://dx.doi.org/10.1016/j.virol.2009.07.028

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