Identification of amino acid residues important for anti-IFN activity of porcine reproductive and respiratory syndrome virus non-structural protein 1

The non-structural protein 1 (nsp1) of porcine reproductive and respiratory syndrome virus is partly responsible for inhibition of type I interferon (IFN) response by the infected host. By performing alanine-scanning mutagenesis, we have identified amino acid residues in nsp1α and nsp1β (the proteol...

Descripción completa

Detalles Bibliográficos
Autores principales: Beura, Lalit K., Subramaniam, Sakthivel, Vu, Hiep L.X., Kwon, Byungjoon, Pattnaik, Asit K., Osorio, Fernando A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7111991/
https://www.ncbi.nlm.nih.gov/pubmed/22995188
http://dx.doi.org/10.1016/j.virol.2012.08.034

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7111991/
https://www.ncbi.nlm.nih.gov/pubmed/22995188
http://dx.doi.org/10.1016/j.virol.2012.08.034

Ejemplares similares