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Identification of amino acid residues important for anti-IFN activity of porcine reproductive and respiratory syndrome virus non-structural protein 1

The non-structural protein 1 (nsp1) of porcine reproductive and respiratory syndrome virus is partly responsible for inhibition of type I interferon (IFN) response by the infected host. By performing alanine-scanning mutagenesis, we have identified amino acid residues in nsp1α and nsp1β (the proteol...

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Detalles Bibliográficos
Autores principales:	Beura, Lalit K., Subramaniam, Sakthivel, Vu, Hiep L.X., Kwon, Byungjoon, Pattnaik, Asit K., Osorio, Fernando A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Inc. 2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7111991/ https://www.ncbi.nlm.nih.gov/pubmed/22995188 http://dx.doi.org/10.1016/j.virol.2012.08.034

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