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Phage-displayed peptides having antigenic similarities with porcine epidemic diarrhea virus (PEDV) neutralizing epitopes

Seven-mer phage random peptide libraries were panned against 2C10, a monoclonal antibody that showed neutralizing activities against PEDV. Recombinant M13 phages displaying the peptides SHRLP(Y/Q)(P/V) or GPRPVTH on the g3p minor coat protein showed strong binding affinity with 2C10 (70% and 30% of...

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Detalles Bibliográficos
Autores principales: Cruz, Deu John M., Kim, Chul-Joong, Shin, Hyun-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7111992/
https://www.ncbi.nlm.nih.gov/pubmed/16950494
http://dx.doi.org/10.1016/j.virol.2006.04.027