Replication of murine coronavirus requires multiple cysteines in the endodomain of spike protein

A conserved cysteine-rich motif located between the transmembrane domain and the endodomain is essential for membrane fusion and assembly of coronavirus spike (S) protein. Here, we proved that three cysteines within the motif, but not dependent on position, are minimally required for the survival of...

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Detalles Bibliográficos
Autores principales: Yang, Jinhua, Lv, Jun, Wang, Yuyan, Gao, Shuang, Yao, Qianqian, Qu, Di, Ye, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7111998/
https://www.ncbi.nlm.nih.gov/pubmed/22424735
http://dx.doi.org/10.1016/j.virol.2012.02.015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7111998/
https://www.ncbi.nlm.nih.gov/pubmed/22424735
http://dx.doi.org/10.1016/j.virol.2012.02.015

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