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Replication of murine coronavirus requires multiple cysteines in the endodomain of spike protein
A conserved cysteine-rich motif located between the transmembrane domain and the endodomain is essential for membrane fusion and assembly of coronavirus spike (S) protein. Here, we proved that three cysteines within the motif, but not dependent on position, are minimally required for the survival of...
Autores principales: | Yang, Jinhua, Lv, Jun, Wang, Yuyan, Gao, Shuang, Yao, Qianqian, Qu, Di, Ye, Rong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Inc.
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7111998/ https://www.ncbi.nlm.nih.gov/pubmed/22424735 http://dx.doi.org/10.1016/j.virol.2012.02.015 |
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