Cargando…

Physiological and molecular triggers for SARS-CoV membrane fusion and entry into host cells

During viral entry, enveloped viruses require the fusion of their lipid envelope with host cell membranes. For coronaviruses, this critical step is governed by the virally-encoded spike (S) protein, a class I viral fusion protein that has several unique features. Coronavirus entry is unusual in that...

Descripción completa

Detalles Bibliográficos
Autores principales: Millet, Jean Kaoru, Whittaker, Gary R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7112017/
https://www.ncbi.nlm.nih.gov/pubmed/29275820
http://dx.doi.org/10.1016/j.virol.2017.12.015