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Structural and functional conservation of cis-acting RNA elements in coronavirus 5'-terminal genome regions

Structure predictions suggest a partial conservation of RNA structure elements in coronavirus terminal genome regions. Here, we determined the structures of stem-loops (SL) 1 and 2 of two alphacoronaviruses, human coronavirus (HCoV) 229E and NL63, by RNA structure probing and studied the functional...

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Detalles Bibliográficos
Autores principales:	Madhugiri, Ramakanth, Karl, Nadja, Petersen, Daniel, Lamkiewicz, Kevin, Fricke, Markus, Wend, Ulrike, Scheuer, Robina, Marz, Manja, Ziebuhr, John
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Inc. 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7112051/ https://www.ncbi.nlm.nih.gov/pubmed/29223446 http://dx.doi.org/10.1016/j.virol.2017.11.025

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