Identification of N-linked glycosylation sites in the spike protein and their functional impact on the replication and infectivity of coronavirus infectious bronchitis virus in cell culture

Spike (S) glycoprotein on the viral envelope is the main determinant of infectivity. The S protein of coronavirus infectious bronchitis virus (IBV) contains 29 putative asparagine(N)-linked glycosylation sites. These post-translational modifications may assist in protein folding and play important r...

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Detalles Bibliográficos
Autores principales: Zheng, Jie, Yamada, Yoshiyuki, Fung, To Sing, Huang, Mei, Chia, Raymond, Liu, Ding Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Inc. 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7112133/
https://www.ncbi.nlm.nih.gov/pubmed/29035787
http://dx.doi.org/10.1016/j.virol.2017.10.003

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