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Identification of N-linked glycosylation sites in the spike protein and their functional impact on the replication and infectivity of coronavirus infectious bronchitis virus in cell culture
Spike (S) glycoprotein on the viral envelope is the main determinant of infectivity. The S protein of coronavirus infectious bronchitis virus (IBV) contains 29 putative asparagine(N)-linked glycosylation sites. These post-translational modifications may assist in protein folding and play important r...
Autores principales: | Zheng, Jie, Yamada, Yoshiyuki, Fung, To Sing, Huang, Mei, Chia, Raymond, Liu, Ding Xiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Published by Elsevier Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7112133/ https://www.ncbi.nlm.nih.gov/pubmed/29035787 http://dx.doi.org/10.1016/j.virol.2017.10.003 |
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