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Induction of Cross-Reactive and Protective Antibody Responses After DNA Vaccination With MHCII-Targeted Stem Domain From Influenza Hemagglutinin

Novel and more broadly protective vaccines against influenza are needed to efficiently meet antigenic drift and shift. Relevant to this end, the stem domain of hemagglutinin (HA) is highly conserved, and antibodies specific for epitopes located to the stem have been demonstrated to be able to confer...

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Detalles Bibliográficos
Autores principales:	Grødeland, Gunnveig, Baranowska-Hustad, Marta, Abadejos, Justin, Blane, Tanya R., Teijaro, John, Nemazee, David, Bogen, Bjarne
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7112135/ https://www.ncbi.nlm.nih.gov/pubmed/32269566 http://dx.doi.org/10.3389/fimmu.2020.00431

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