Vaccination with single plasmid DNA encoding IL-12 and antigens of severe fever with thrombocytopenia syndrome virus elicits complete protection in IFNAR knockout mice

Severe fever with thrombocytopenia syndrome (SFTS) is an emerging tick-borne disease caused by SFTS virus (SFTSV) infection. Despite a gradual increase of SFTS cases and high mortality in endemic regions, no specific viral therapy nor vaccine is available. Here, we developed a single recombinant pla...

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Detalles Bibliográficos
Autores principales: Kang, Jun-Gu, Jeon, Kyeongseok, Choi, Hooncheol, Kim, Yuri, Kim, Hong-Il, Ro, Hyo-Jin, Seo, Yong Bok, Shin, Jua, Chung, Junho, Jeon, Yoon Kyung, Kim, Yang Soo, Lee, Keun Hwa, Cho, Nam-Hyuk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7112229/
https://www.ncbi.nlm.nih.gov/pubmed/32196487
http://dx.doi.org/10.1371/journal.pntd.0007813

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7112229/
https://www.ncbi.nlm.nih.gov/pubmed/32196487
http://dx.doi.org/10.1371/journal.pntd.0007813

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