Efficacy of single versus four repeated doses of praziquantel against Schistosoma mansoni infection in school-aged children from Côte d'Ivoire based on Kato-Katz and POC-CCA: An open-label, randomised controlled trial (RePST)

BACKGROUND: Preventive chemotherapy with praziquantel (PZQ) is the cornerstone of schistosomiasis control. However, a single dose of PZQ (40 mg/kg) does not cure all infections. Repeated doses of PZQ at short intervals might increase efficacy in terms of cure rate (CR) and intensity reduction rate (...

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Detalles Bibliográficos
Autores principales: Hoekstra, Pytsje T., Casacuberta-Partal, Miriam, van Lieshout, Lisette, Corstjens, Paul L. A. M., Tsonaka, Roula, Assaré, Rufin K., Silué, Kigbafori D., Meité, Aboulaye, N’Goran, Eliézer K., N’Gbesso, Yves K., Amoah, Abena S., Roestenberg, Meta, Knopp, Stefanie, Utzinger, Jürg, Coulibaly, Jean T., van Dam, Govert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7112237/
https://www.ncbi.nlm.nih.gov/pubmed/32196506
http://dx.doi.org/10.1371/journal.pntd.0008189

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