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WHIMP links the actin nucleation machinery to Src-family kinase signaling during protrusion and motility

Cell motility is governed by cooperation between the Arp2/3 complex and nucleation-promoting factors from the Wiskott-Aldrich Syndrome Protein (WASP) family, which together assemble actin filament networks to drive membrane protrusion. Here we identify WHIMP (WAVE Homology In Membrane Protrusions) a...

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Detalles Bibliográficos
Autores principales: Kabrawala, Shail, Zimmer, Margaret D., Campellone, Kenneth G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7112243/
https://www.ncbi.nlm.nih.gov/pubmed/32196488
http://dx.doi.org/10.1371/journal.pgen.1008694

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