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Recent Advances in the Discovery of Deubiquitinating Enzyme Inhibitors

This review examines the small molecules described over the past decade as inhibitors of any of the approximately 100 human deubiquitinating enzymes (DUBs). Structures from patent publications as well as from the primary literature are included. Inhibitors of two viral DUBs are also described since...

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Detalles Bibliográficos
Autor principal: Kemp, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7112275/
https://www.ncbi.nlm.nih.gov/pubmed/26852935
http://dx.doi.org/10.1016/bs.pmch.2015.10.002