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The Role of CD4 T Cells in the Pathogenesis of Multiple Sclerosis

T lymphocytes play a central role in the pathogenesis of multiple sclerosis (MS) (Zhang et al., 1992). Both CD4+ and CD8+ T cells have been demonstrated in MS lesions, with CD4+ T cells predominating in acute lesions and CD8+ T cells being observed more frequently in chronic lesions (Raine, 1994). A...

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Detalles Bibliográficos
Autor principal: Chitnis, Tanuja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7112308/
https://www.ncbi.nlm.nih.gov/pubmed/17531837
http://dx.doi.org/10.1016/S0074-7742(07)79003-7