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Functional Genomic Strategies for Elucidating Human–Virus Interactions: Will CRISPR Knockout RNAi and Haploid Cells?

Over the last several years a wealth of transformative human–virus interaction discoveries have been produced using loss-of-function functional genomics. These insights have greatly expanded our understanding of how human pathogenic viruses exploit our cells to replicate. Two technologies have been...

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Detalles Bibliográficos
Autores principales: Perreira, Jill M., Meraner, Paul, Brass, Abraham L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7112329/
https://www.ncbi.nlm.nih.gov/pubmed/26997589
http://dx.doi.org/10.1016/bs.aivir.2015.11.001