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Programmed –1 Frameshifting by Kinetic Partitioning during Impeded Translocation

Programmed –1 ribosomal frameshifting (−1PRF) is an mRNA recoding event utilized by cells to enhance the information content of the genome and to regulate gene expression. The mechanism of –1PRF and its timing during translation elongation are unclear. Here, we identified the steps that govern –1PRF...

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Detalles Bibliográficos
Autores principales: Caliskan, Neva, Katunin, Vladimir I., Belardinelli, Riccardo, Peske, Frank, Rodnina, Marina V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7112342/
https://www.ncbi.nlm.nih.gov/pubmed/24949973
http://dx.doi.org/10.1016/j.cell.2014.04.041