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Programmed –1 Frameshifting by Kinetic Partitioning during Impeded Translocation
Programmed –1 ribosomal frameshifting (−1PRF) is an mRNA recoding event utilized by cells to enhance the information content of the genome and to regulate gene expression. The mechanism of –1PRF and its timing during translation elongation are unclear. Here, we identified the steps that govern –1PRF...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Inc.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7112342/ https://www.ncbi.nlm.nih.gov/pubmed/24949973 http://dx.doi.org/10.1016/j.cell.2014.04.041 |