Construction, expression and antiviral activity analysis of recombinant adenovirus expressing human IFITM3 in vitro

Interferon-inducible transmembrane protein 3 (IFITM3) inhibits the replication of multiple pathogenic viruses by blocking their entry. In this study, we constructed a shuttle plasmid, harboring human IFITM3. Thereafter, recombinant adenovirus rAd5-IFITM3 was obtained by co-transfection of the linear...

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Detalles Bibliográficos
Autores principales: Du, Shouwen, Jiang, Yinyue, Xu, Wang, Bai, Jieying, Tian, Mingyao, Wang, Maopeng, Wang, Yuhang, Cao, Tingting, Song, Lina, Jiang, Yuhang, Chen, Jing, Fu, Tingting, Hao, Penfeng, Li, Tiyuan, Wu, Shipin, Ren, Linzhu, Jin, Ningyi, Li, Chang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7112391/
https://www.ncbi.nlm.nih.gov/pubmed/30914370
http://dx.doi.org/10.1016/j.ijbiomac.2019.03.161

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