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The antiviral activity of poly-γ-glutamic acid, a polypeptide secreted by Bacillus sp., through induction of CD14-dependent type I interferon responses
Poly-γ-glutamic acid (γ-PGA) is an anionic polypeptide secreted by Bacillus sp. that has been shown to activate immune cells through interactions with toll-like receptor 4 (TLR4). However, its ability to induce the type I interferon (IFN) response has not yet been characterized. Here, we demonstrate...
Autores principales: | Lee, Wooseong, Lee, Seung-Hoon, Ahn, Dae-Gyun, Cho, Hee, Sung, Moon-Hee, Han, Seung Hyun, Oh, Jong-Won |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Ltd.
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7112489/ https://www.ncbi.nlm.nih.gov/pubmed/24016850 http://dx.doi.org/10.1016/j.biomaterials.2013.08.067 |
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