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Cytokines and synthetic double-stranded RNA augment the T helper 1 immune response of swine to porcine reproductive and respiratory syndrome virus
Immunization of pigs with a modified live porcine reproductive and respiratory syndrome virus (PRRSV) vaccine initially elicits a weak interferon (IFN)-γ response. To improve the immune response, an adjuvant consisting of plasmid encoding either porcine interleukin (IL)-12 or IFN-α was co-administer...
Autores principales: | Meier, William A., Husmann, Robert J., Schnitzlein, William M., Osorio, Fernando A., Lunney, Joan K., Zuckermann, Federico A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier B.V.
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7112576/ https://www.ncbi.nlm.nih.gov/pubmed/15507313 http://dx.doi.org/10.1016/j.vetimm.2004.09.012 |
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