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SARS spike protein induces phenotypic conversion of human B cells to macrophage-like cells

Massive aggregations of macrophages are frequently detected in afflicted lungs of patients with severe acute respiratory syndrome-associated coronavirus (SARS-CoV) infection. In vitro, ectopic expression of transcription factors, in particular CCAAT/enhancer-binding protein alpha (C/EBPα) and C/EBPβ...

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Detalles Bibliográficos
Autores principales: Chiang, Shu-Fen, Lin, Tze-Yi, Chow, Kuan-Chih, Chiou, Shiow-Her
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7112600/
https://www.ncbi.nlm.nih.gov/pubmed/20667598
http://dx.doi.org/10.1016/j.molimm.2010.06.014