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Evolutionary aspects of lipoxygenases and genetic diversity of human leukotriene signaling

Leukotrienes are pro-inflammatory lipid mediators, which are biosynthesized via the lipoxygenase pathway of the arachidonic acid cascade. Lipoxygenases form a family of lipid peroxidizing enzymes and human lipoxygenase isoforms have been implicated in the pathogenesis of inflammatory, hyperprolifera...

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Detalles Bibliográficos
Autores principales: Horn, Thomas, Adel, Susan, Schumann, Ralf, Sur, Saubashya, Kakularam, Kumar Reddy, Polamarasetty, Aparoy, Redanna, Pallu, Kuhn, Hartmut, Heydeck, Dagmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7112624/
https://www.ncbi.nlm.nih.gov/pubmed/25435097
http://dx.doi.org/10.1016/j.plipres.2014.11.001

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