Salt bridge-forming residues positioned over viral peptides presented by MHC class I impacts T-cell recognition in a binding-dependent manner

The viral peptides presentation by major histocompatibility complex class I (MHC I) molecules play a pivotal role in T-cell recognition and the subsequent virus clearance. This process is delicately adjusted by the variant residues of MHC I, especially the residues in the peptide binding groove (PBG...

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Detalles Bibliográficos
Autores principales: Ji, Wei, Niu, Ling, Peng, Weiyu, Zhang, Yongli, Cheng, Hao, Gao, Feng, Shi, Yi, Qi, Jianxun, Gao, George F., Liu, William J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7112684/
https://www.ncbi.nlm.nih.gov/pubmed/31226552
http://dx.doi.org/10.1016/j.molimm.2019.06.005

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