IL-27 signaling activates skin cells to induce innate antiviral proteins and protects against Zika virus infection

In the skin, antiviral proteins and other immune molecules serve as the first line of innate antiviral defense. Here, we identify and characterize the induction of cutaneous innate antiviral proteins in response to IL-27 and its functional role during cutaneous defense against Zika virus infection....

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Detalles Bibliográficos
Autores principales: Kwock, Jeffery T., Handfield, Chelsea, Suwanpradid, Jutamas, Hoang, Peter, McFadden, Michael J., Labagnara, Kevin F., Floyd, Lauren, Shannon, Jessica, Uppala, Ranjitha, Sarkar, Mrinal K., Gudjonsson, Johann E., Corcoran, David L., Lazear, Helen M., Sempowski, Gregory, Horner, Stacy M., MacLeod, Amanda S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7112749/
https://www.ncbi.nlm.nih.gov/pubmed/32270034
http://dx.doi.org/10.1126/sciadv.aay3245

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