ENL initiates multivalent phase separation of the super elongation complex (SEC) in controlling rapid transcriptional activation

Release of paused RNA polymerase II (Pol II) requires incorporation of the positive transcription elongation factor b (P-TEFb) into the super elongation complex (SEC), thus resulting in rapid yet synchronous transcriptional activation. However, the mechanism underlying dynamic transition of P-TEFb f...

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Detalles Bibliográficos
Autores principales: Guo, Chenghao, Che, Zhuanzhuan, Yue, Junjie, Xie, Peng, Hao, Shaohua, Xie, Wei, Luo, Zhuojuan, Lin, Chengqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7112754/
https://www.ncbi.nlm.nih.gov/pubmed/32270036
http://dx.doi.org/10.1126/sciadv.aay4858

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