Epitope-directed antibody selection by site-specific photocrosslinking

Currently, there are no methods available offering solutions to select and identify antibodies binding to a specific conformational epitope of an antigen. Here, we developed a method to allow epitope-directed antibody selection from a phage display library by photocrosslinking bound antibodies to a...

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Detalles Bibliográficos
Autores principales: Chen, Longxin, Zhu, Chaoyang, Guo, Hui, Li, Runting, Zhang, Limeng, Xing, Zhenzhen, Song, Yue, Zhang, Zihan, Wang, Fuping, Liu, Xiaofeng, Zhang, Yuhan, Ma, Runlin Z., Wang, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7112767/
https://www.ncbi.nlm.nih.gov/pubmed/32270046
http://dx.doi.org/10.1126/sciadv.aaz7825

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