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H5N1 Oseltamivir-resistance detection by real-time PCR using two high sensitivity labeled TaqMan probes
A single amino acid substitution, from histidine to tyrosine at position 274 of the neuraminidase gene has converted Oseltamivir sensitive H5N1 influenza A virus into a resistant strain. Currently, Oseltamivir is being stockpiled in many countries potentially affected by the influenza A virus subtyp...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier B.V.
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7112789/ https://www.ncbi.nlm.nih.gov/pubmed/17055070 http://dx.doi.org/10.1016/j.jviromet.2006.09.007 |