Structure–function analysis and molecular modeling of DNase catalytic antibodies

There is great interest in the antibodies-to-DNA transformation, since this change is characteristic of autoimmune diseases and contributes to its pathology. After immunization and fusions, 14 hybridomas bearing DNA-hydrolysis activity against pUC19 plasmid DNA were obtained. Genes coding for V(H) a...

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Detalles Bibliográficos
Autores principales: Zein, Haggag S., Teixeira da Silva, Jaime A., Miyatake, Kazutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7112887/
https://www.ncbi.nlm.nih.gov/pubmed/20097230
http://dx.doi.org/10.1016/j.imlet.2010.01.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7112887/
https://www.ncbi.nlm.nih.gov/pubmed/20097230
http://dx.doi.org/10.1016/j.imlet.2010.01.004

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