A chimeric multi-epitope DNA vaccine elicited specific antibody response against severe acute respiratory syndrome-associated coronavirus which attenuated the virulence of SARS-CoV in vitro

Epitope-based vaccines designed to induce antibody responses specific for severe acute respiratory syndrome-associated coronavirus (SARS-CoV) are being developed as a means for increasing vaccine potency. In this study, we identified four B cell epitopes from the spike (S) and membrane (M) protein t...

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Detalles Bibliográficos
Autores principales: Wang, Xiaohua, Xu, Wei, Tong, Deyan, Ni, Jing, Gao, Haifeng, Wang, Ying, Chu, Yiwei, Li, Pingping, Yang, Xiaoming, Xiong, Sidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2008
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7112888/
https://www.ncbi.nlm.nih.gov/pubmed/18533276
http://dx.doi.org/10.1016/j.imlet.2008.04.005

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