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Targeting the COX1/2-Driven thromboxane A2 pathway suppresses Barrett's esophagus and esophageal adenocarcinoma development

BACKGROUND: Barrett's esophagus (BE), a complication of gastroesophageal reflux disease (GERD), predisposes patients to esophageal adenocarcinoma (EAC). Reliable biomarkers for early detection and discovery of potential drug targets are urgently needed for improved BE and EAC patient outcomes....

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Detalles Bibliográficos
Autores principales: Zhang, Tianshun, Wang, Qiushi, Ma, Wei-Ya, Wang, Keke, Chang, Xiaoyu, Johnson, Michele L., Bai, Ruihua, Bode, Ann M., Foster, Nathan R., Falk, Gary W., Limburg, Paul J., Iyer, Prasad G., Dong, Zigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7113183/
https://www.ncbi.nlm.nih.gov/pubmed/31707149
http://dx.doi.org/10.1016/j.ebiom.2019.10.038