Pretreatment Tumor DNA Sequencing of KIT and PDGFRA in Endosonography-Guided Biopsies Optimizes the Preoperative Management of Gastrointestinal Stromal Tumors

BACKGROUND: Neoadjuvant tyrosine kinase inhibitor (TKI) therapy increases the chance of organ-preserving, radical resection in selected patients with gastrointestinal stromal tumors (GISTs). We aimed to evaluate systematic, immediate DNA sequencing of KIT and PDGFRA in pretreatment GIST tissue to gu...

Descripción completa

Detalles Bibliográficos
Autores principales: Hedenström, Per, Andersson, Carola, Sjövall, Henrik, Enlund, Fredrik, Nilsson, Ola, Nilsson, Bengt, Sadik, Riadh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7113213/
https://www.ncbi.nlm.nih.gov/pubmed/32124386
http://dx.doi.org/10.1007/s40291-020-00451-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7113213/
https://www.ncbi.nlm.nih.gov/pubmed/32124386
http://dx.doi.org/10.1007/s40291-020-00451-0

Ejemplares similares