Cargando…

Synthesis of Conductive Carbon Aerogels Decorated with β-Tricalcium Phosphate Nanocrystallites

There has been substantial interest in research aimed at conductive carbon-based supports since the discovery that the electrical stimulus can have dramatic effect on cell behavior. Among these carbon-aerogels decorated with biocompatible polymers were suggested as future materials for tissue engine...

Descripción completa

Detalles Bibliográficos
Autores principales: Tevlek, Atakan, Atya, Abdulraheem M. N., Almemar, Muhannad, Duman, Memed, Gokcen, Dincer, Ganin, Alexey Y., Yiu, Humphrey H. P., Aydin, Halil M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7113289/
https://www.ncbi.nlm.nih.gov/pubmed/32238872
http://dx.doi.org/10.1038/s41598-020-62822-1
_version_ 1783513640823947264
author Tevlek, Atakan
Atya, Abdulraheem M. N.
Almemar, Muhannad
Duman, Memed
Gokcen, Dincer
Ganin, Alexey Y.
Yiu, Humphrey H. P.
Aydin, Halil M.
author_facet Tevlek, Atakan
Atya, Abdulraheem M. N.
Almemar, Muhannad
Duman, Memed
Gokcen, Dincer
Ganin, Alexey Y.
Yiu, Humphrey H. P.
Aydin, Halil M.
author_sort Tevlek, Atakan
collection PubMed
description There has been substantial interest in research aimed at conductive carbon-based supports since the discovery that the electrical stimulus can have dramatic effect on cell behavior. Among these carbon-aerogels decorated with biocompatible polymers were suggested as future materials for tissue engineering. However, high reaction temperatures required for the synthesis of the aerogels tend to impair the stability of the polymeric networks. Herein, we report a synthetic route towards carbon-aerogel scaffolds decorated with biocompatible ceramic nanoparticles of tricalcium phosphate. The composites can be prepared at temperature as high as 1100 °C without significant effect on the morphology of the composite which is comparable with the original aerogel framework. Although the conductivity of the composites tends to decrease with the increasing ceramic content the measured conductivity values are similar to those previously reported on polymer-functionalized carbon-aerogels. The cell culture study revealed that the developed constructs support cell proliferation and provide good cell attachment suggesting them as potentially good candidates for tissue-engineering applications.
format Online
Article
Text
id pubmed-7113289
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Nature Publishing Group UK
record_format MEDLINE/PubMed
spelling pubmed-71132892020-04-06 Synthesis of Conductive Carbon Aerogels Decorated with β-Tricalcium Phosphate Nanocrystallites Tevlek, Atakan Atya, Abdulraheem M. N. Almemar, Muhannad Duman, Memed Gokcen, Dincer Ganin, Alexey Y. Yiu, Humphrey H. P. Aydin, Halil M. Sci Rep Article There has been substantial interest in research aimed at conductive carbon-based supports since the discovery that the electrical stimulus can have dramatic effect on cell behavior. Among these carbon-aerogels decorated with biocompatible polymers were suggested as future materials for tissue engineering. However, high reaction temperatures required for the synthesis of the aerogels tend to impair the stability of the polymeric networks. Herein, we report a synthetic route towards carbon-aerogel scaffolds decorated with biocompatible ceramic nanoparticles of tricalcium phosphate. The composites can be prepared at temperature as high as 1100 °C without significant effect on the morphology of the composite which is comparable with the original aerogel framework. Although the conductivity of the composites tends to decrease with the increasing ceramic content the measured conductivity values are similar to those previously reported on polymer-functionalized carbon-aerogels. The cell culture study revealed that the developed constructs support cell proliferation and provide good cell attachment suggesting them as potentially good candidates for tissue-engineering applications. Nature Publishing Group UK 2020-04-01 /pmc/articles/PMC7113289/ /pubmed/32238872 http://dx.doi.org/10.1038/s41598-020-62822-1 Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Tevlek, Atakan
Atya, Abdulraheem M. N.
Almemar, Muhannad
Duman, Memed
Gokcen, Dincer
Ganin, Alexey Y.
Yiu, Humphrey H. P.
Aydin, Halil M.
Synthesis of Conductive Carbon Aerogels Decorated with β-Tricalcium Phosphate Nanocrystallites
title Synthesis of Conductive Carbon Aerogels Decorated with β-Tricalcium Phosphate Nanocrystallites
title_full Synthesis of Conductive Carbon Aerogels Decorated with β-Tricalcium Phosphate Nanocrystallites
title_fullStr Synthesis of Conductive Carbon Aerogels Decorated with β-Tricalcium Phosphate Nanocrystallites
title_full_unstemmed Synthesis of Conductive Carbon Aerogels Decorated with β-Tricalcium Phosphate Nanocrystallites
title_short Synthesis of Conductive Carbon Aerogels Decorated with β-Tricalcium Phosphate Nanocrystallites
title_sort synthesis of conductive carbon aerogels decorated with β-tricalcium phosphate nanocrystallites
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7113289/
https://www.ncbi.nlm.nih.gov/pubmed/32238872
http://dx.doi.org/10.1038/s41598-020-62822-1
work_keys_str_mv AT tevlekatakan synthesisofconductivecarbonaerogelsdecoratedwithbtricalciumphosphatenanocrystallites
AT atyaabdulraheemmn synthesisofconductivecarbonaerogelsdecoratedwithbtricalciumphosphatenanocrystallites
AT almemarmuhannad synthesisofconductivecarbonaerogelsdecoratedwithbtricalciumphosphatenanocrystallites
AT dumanmemed synthesisofconductivecarbonaerogelsdecoratedwithbtricalciumphosphatenanocrystallites
AT gokcendincer synthesisofconductivecarbonaerogelsdecoratedwithbtricalciumphosphatenanocrystallites
AT ganinalexeyy synthesisofconductivecarbonaerogelsdecoratedwithbtricalciumphosphatenanocrystallites
AT yiuhumphreyhp synthesisofconductivecarbonaerogelsdecoratedwithbtricalciumphosphatenanocrystallites
AT aydinhalilm synthesisofconductivecarbonaerogelsdecoratedwithbtricalciumphosphatenanocrystallites