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Synthesis of Conductive Carbon Aerogels Decorated with β-Tricalcium Phosphate Nanocrystallites
There has been substantial interest in research aimed at conductive carbon-based supports since the discovery that the electrical stimulus can have dramatic effect on cell behavior. Among these carbon-aerogels decorated with biocompatible polymers were suggested as future materials for tissue engine...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7113289/ https://www.ncbi.nlm.nih.gov/pubmed/32238872 http://dx.doi.org/10.1038/s41598-020-62822-1 |
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author | Tevlek, Atakan Atya, Abdulraheem M. N. Almemar, Muhannad Duman, Memed Gokcen, Dincer Ganin, Alexey Y. Yiu, Humphrey H. P. Aydin, Halil M. |
author_facet | Tevlek, Atakan Atya, Abdulraheem M. N. Almemar, Muhannad Duman, Memed Gokcen, Dincer Ganin, Alexey Y. Yiu, Humphrey H. P. Aydin, Halil M. |
author_sort | Tevlek, Atakan |
collection | PubMed |
description | There has been substantial interest in research aimed at conductive carbon-based supports since the discovery that the electrical stimulus can have dramatic effect on cell behavior. Among these carbon-aerogels decorated with biocompatible polymers were suggested as future materials for tissue engineering. However, high reaction temperatures required for the synthesis of the aerogels tend to impair the stability of the polymeric networks. Herein, we report a synthetic route towards carbon-aerogel scaffolds decorated with biocompatible ceramic nanoparticles of tricalcium phosphate. The composites can be prepared at temperature as high as 1100 °C without significant effect on the morphology of the composite which is comparable with the original aerogel framework. Although the conductivity of the composites tends to decrease with the increasing ceramic content the measured conductivity values are similar to those previously reported on polymer-functionalized carbon-aerogels. The cell culture study revealed that the developed constructs support cell proliferation and provide good cell attachment suggesting them as potentially good candidates for tissue-engineering applications. |
format | Online Article Text |
id | pubmed-7113289 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-71132892020-04-06 Synthesis of Conductive Carbon Aerogels Decorated with β-Tricalcium Phosphate Nanocrystallites Tevlek, Atakan Atya, Abdulraheem M. N. Almemar, Muhannad Duman, Memed Gokcen, Dincer Ganin, Alexey Y. Yiu, Humphrey H. P. Aydin, Halil M. Sci Rep Article There has been substantial interest in research aimed at conductive carbon-based supports since the discovery that the electrical stimulus can have dramatic effect on cell behavior. Among these carbon-aerogels decorated with biocompatible polymers were suggested as future materials for tissue engineering. However, high reaction temperatures required for the synthesis of the aerogels tend to impair the stability of the polymeric networks. Herein, we report a synthetic route towards carbon-aerogel scaffolds decorated with biocompatible ceramic nanoparticles of tricalcium phosphate. The composites can be prepared at temperature as high as 1100 °C without significant effect on the morphology of the composite which is comparable with the original aerogel framework. Although the conductivity of the composites tends to decrease with the increasing ceramic content the measured conductivity values are similar to those previously reported on polymer-functionalized carbon-aerogels. The cell culture study revealed that the developed constructs support cell proliferation and provide good cell attachment suggesting them as potentially good candidates for tissue-engineering applications. Nature Publishing Group UK 2020-04-01 /pmc/articles/PMC7113289/ /pubmed/32238872 http://dx.doi.org/10.1038/s41598-020-62822-1 Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Tevlek, Atakan Atya, Abdulraheem M. N. Almemar, Muhannad Duman, Memed Gokcen, Dincer Ganin, Alexey Y. Yiu, Humphrey H. P. Aydin, Halil M. Synthesis of Conductive Carbon Aerogels Decorated with β-Tricalcium Phosphate Nanocrystallites |
title | Synthesis of Conductive Carbon Aerogels Decorated with β-Tricalcium Phosphate Nanocrystallites |
title_full | Synthesis of Conductive Carbon Aerogels Decorated with β-Tricalcium Phosphate Nanocrystallites |
title_fullStr | Synthesis of Conductive Carbon Aerogels Decorated with β-Tricalcium Phosphate Nanocrystallites |
title_full_unstemmed | Synthesis of Conductive Carbon Aerogels Decorated with β-Tricalcium Phosphate Nanocrystallites |
title_short | Synthesis of Conductive Carbon Aerogels Decorated with β-Tricalcium Phosphate Nanocrystallites |
title_sort | synthesis of conductive carbon aerogels decorated with β-tricalcium phosphate nanocrystallites |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7113289/ https://www.ncbi.nlm.nih.gov/pubmed/32238872 http://dx.doi.org/10.1038/s41598-020-62822-1 |
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