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Molecular basis of ALK1-mediated signalling by BMP9/BMP10 and their prodomain-bound forms

Activin receptor-like kinase 1 (ALK1)-mediated endothelial cell signalling in response to bone morphogenetic protein 9 (BMP9) and BMP10 is of significant importance in cardiovascular disease and cancer. However, detailed molecular mechanisms of ALK1-mediated signalling remain unclear. Here, we repor...

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Detalles Bibliográficos
Autores principales:	Salmon, Richard M., Guo, Jingxu, Wood, Jennifer H., Tong, Zhen, Beech, John S., Lawera, Aleksandra, Yu, Minmin, Grainger, David J., Reckless, Jill, Morrell, Nicholas W., Li, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7113306/ https://www.ncbi.nlm.nih.gov/pubmed/32238803 http://dx.doi.org/10.1038/s41467-020-15425-3

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